An 11-year-old boy suffering from severe heart failure and shock due to Multisystem Inflammatory Syndrome in Children (MIS-C) was successfully treated at Amrita Hospital in Kochi with ECMO, which is akin to heart-lung bypass machine used in open-heart surgery, saving his life from the dreaded disease that appears to be linked to Covid-19. Amrita Hospital doctors are warning of a wave of MIS-C across South India which may hit children in a big way. Adhik’s case is an early warning of this, they say. The child Adhik, hailing from Kedamangalam in Paravur (Ernakulam district), is one of the rarest patients in India to be put on ECMO (Extra Corporeal Membrane Oxygenation) for MIS-C. ECMO pumps and oxygenates a patient's blood outside the body, allowing the heart and lungs to rest. When a patient is connected to an ECMO, blood flows through tubing to an artificial lung in the machine that adds oxygen and takes out carbon dioxide; then the blood is warmed to body temperature and pumped back into the body. ECMO is today saving many patients from Covid-19 and post-Covid complications. Adhik was referred to Amrita Hospital in a serious condition. He most likely had an asymptomatic Covid-19 or was exposed to Covid-19 in the weeks preceding the presentation as widened by positive antibody titers to Covid-19 in his blood. MIS-C had over the last one week severely affected his heart muscles, which were inflamed and unable to pump blood. His blood pressure had dropped to extremely low levels. The condition would have been fatal if not treated promptly. On arrival at the hospital, Amrita doctors put him on a ventilator without delay. Said Dr Suma Balan, Consultant Pediatrician and Pediatric Rheumatologist, Rheumatology and Clinical Immunology, Amrita Hospital, Kochi: “Putting a very sick child with low blood pressure and poor heart on ventilator needs a high degree of skill and training from a Pediatric Intensivist. The child also required special lines to be inserted into his large veins, so that medicines to elevate his blood pressure could be safely administered without needing to prick him all the time.